Hi, Amanda. Love your website. Helping lots with part one prep. Just a note on the 2009b(6) answer above. Under oxytocin: MoA is incorrect. Oxytocin receptors are Gq, (IP3/DAG – incr Calcium – increase Calmodulin interaction – increase force of contraction). The answer says it acts by increase in gK causing increased excitability, (which doesn’t make sense since this would hyperpolarise cell). Have I missed something?
Thanks again for the site. I will endeavour to pay-it-forward and provide a model answer for the next SAQ’s.
Hi, Amanda. Love your website. Helping lots with part one prep. Just a note on the 2009b(6) answer above. Under oxytocin: MoA is incorrect. Oxytocin receptors are Gq, (IP3/DAG – incr Calcium – increase Calmodulin interaction – increase force of contraction). The answer says it acts by increase in gK causing increased excitability, (which doesn’t make sense since this would hyperpolarise cell). Have I missed something?
Thanks again for the site. I will endeavour to pay-it-forward and provide a model answer for the next SAQ’s.
Cheers,
e
Eddie
September 15, 2013 at 12:05 am
Thanks for the heads up – correction has been made.
primarysaqs
March 4, 2014 at 3:27 pm